Safb2tm1So
Targeted Allele Detail
|
Symbol: |
Safb2tm1So |
Name: |
scaffold attachment factor B2; targeted mutation 1, Steffi Oesterreich |
MGI ID: |
MGI:5695073 |
Gene: |
Safb2 Location: Chr17:56867965-56891585 bp, - strand Genetic Position: Chr17, 29.39 cM
|
Alliance: |
Safb2tm1So page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:225512
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
129
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: Exons 4-10 were replaced by an IRES-lacZ-SV40pA (beta-galactosidase) marker and a PGK-Neomycin-bGHpA selection cassette. Northern blot analysis indicated that no detectable transcript encoding the C-terminus is expressed from this allele. The N-terminus is expressed together with the introduced lacZ gene. LacZ is expressed in Sertoli cells.
(J:225512)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Safb2 Mutation: |
38 strains or lines available
|
|
Original: |
J:225512 Jiang S, et al., Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1. Dis Model Mech. 2015 Sep 1;8(9):1121-7 |
All: |
1 reference(s) |
|