Mki67^em1Dfis
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mki67^em1Dfis
• Name: antigen identified by monoclonal antibody Ki 67; endonuclease-mediated mutation 1, Daniel Fisher
• MGI ID: MGI:5695662
• Synonyms: Mki67^{2-nt delta}, Mki67^2ntdelta
• Gene: Mki67 Location: Chr7:135291513-135318090 bp, - strand Genetic Position: Chr7, 81.32 cM, cytoband F3-F5
• Alliance: Mki67^em1Dfis page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Hypomorph)
• Mutation: Intragenic deletion
• TALEN technology was used to delete the 2 nucleotides after the initiation ATG codon. (J:235309)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mki67 Mutation: 146 strains or lines available

References

• Original: J:235309 Sobecki M, et al., The cell proliferation antigen Ki-67 organises heterochromatin. Elife. 2016;5:e13722
• All: 3 reference(s)