Dbx1^tm2Jcor
Targeted Allele Detail

Summary

• Symbol: Dbx1^tm2Jcor
• Name: developing brain homeobox 1; targeted mutation 2, Joshua Corbin
• MGI ID: MGI:5696633
• Synonyms: Dbx1^flox
• Gene: Dbx1 Location: Chr7:49281247-49286583 bp, - strand Genetic Position: Chr7, 31.44 cM
• Alliance: Dbx1^tm2Jcor page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221571
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector contains a loxP site upstream of exon 2 and a loxP site downstream of exon 4 followed by an FRT-flanked neomycin cassette. (J:221571)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dbx1 Mutation: 25 strains or lines available

References

• Original: J:221571 Sokolowski K, et al., Specification of select hypothalamic circuits and innate behaviors by the embryonic patterning gene dbx1. Neuron. 2015 Apr 22;86(2):403-16
• All: 2 reference(s)