Slc39a1^tm1Gka
Targeted Allele Detail

Summary

• Symbol: Slc39a1^tm1Gka
• Name: solute carrier family 39 (zinc transporter), member 1; targeted mutation 1, Glen K Andrews
• MGI ID: MGI:5696637
• Synonyms: ZIP1^-, ZIP1^- pre-Cre
• Gene: Slc39a1 Location: Chr3:90155512-90160923 bp, + strand Genetic Position: Chr3, 39.21 cM
• Alliance: Slc39a1^tm1Gka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:108627
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: The enhanced green fluorescent protein (EGFP) coding sequence, followed by a termination codon, a polyadenylation signal and a loxP-flanked MC1-neo cassette, was inserted into the gene immediately following and in frame with the translation initiation codon in the second exon. (J:108627)

Expression

In Mice Carrying this Mutation:

11 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc39a1 Mutation: 22 strains or lines available

References

• Original: J:108627 Dufner-Beattie J, et al., Mouse ZIP1 and ZIP3 genes together are essential for adaptation to dietary zinc deficiency during pregnancy. Genesis. 2006 May;44(5):239-51
• All: 2 reference(s)