Btg2^{tm1.1(cre/ERT2)Wbh}
Targeted Allele Detail

Summary

• Symbol: Btg2^{tm1.1(cre/ERT2)Wbh}
• Name: BTG anti-proliferation factor 2; targeted mutation 1.1, Weiland B Huttner
• MGI ID: MGI:5696980
• Synonyms: Tis21-CreER^T2
• Gene: Btg2 Location: Chr1:134002908-134006858 bp, - strand Genetic Position: Chr1, 58.1 cM
• Alliance: Btg2^{tm1.1(cre/ERT2)Wbh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225790
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutations: Insertion, Intragenic deletion
• Btg2^{tm1.1(cre/ERT2)Wbh} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Btg2 (MGI:108384)

• Mutation details: The targeting construct replaced exon 1 with an inducible cre recombinase gene (cre/ERT2), polyadenylation sequence, HSV tag and FRT-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:225790)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Btg2 (mouse) Summary of all recombinase alleles driven by Btg2. Comparative matrix view of recombinase activities Alliance mouse Btg2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btg2 Mutation: 16 strains or lines available

References

• Original: J:225790 Wong FK, et al., Sustained Pax6 Expression Generates Primate-like Basal Radial Glia in Developing Mouse Neocortex. PLoS Biol. 2015 Aug;13(8):e1002217
• All: 2 reference(s)