Tg(Acta2-cre/ERT2)1Tcw
Transgene Detail

Summary

• Symbol: Tg(Acta2-cre/ERT2)1Tcw
• Name: transgene insertion 1, Timothy C Wang
• MGI ID: MGI:5696986
• Synonyms: Acta2-CreER^T
• Transgene: Tg(Acta2-cre/ERT2)1Tcw Location: unknown
• Alliance: Tg(Acta2-cre/ERT2)1Tcw page

Transgene origin

• Strain of Origin: CBA x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Acta2-cre/ERT2)1Tcw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Acta2 (MGI:87909)

• Mutation details: The BAC RP24-374H8 was engineered to contain an inducible cre recombinase gene (cre/ERT2) inserted into the start site of Acta2. Line 1 was generated. (J:226253)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Acta2 (mouse) Summary of all recombinase alleles driven by Acta2. Comparative matrix view of recombinase activities Alliance mouse Acta2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:226253 Manieri NA, et al., Mucosally transplanted mesenchymal stem cells stimulate intestinal healing by promoting angiogenesis. J Clin Invest. 2015 Sep;125(9):3606-18
• All: 2 reference(s)