Dmp1^{tm2(EGFP/cre/ERT2)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Dmp1^{tm2(EGFP/cre/ERT2)Wtsi}
• Name: dentin matrix protein 1; targeted mutation 1, Wellcome Trust Sanger Institute
• MGI ID: MGI:5697479
• Gene: Dmp1 Location: Chr5:104350479-104361968 bp, + strand Genetic Position: Chr5, 50.61 cM
• Alliance: Dmp1^{tm2(EGFP/cre/ERT2)Wtsi} page

Mutation origin

• Mutant Cell Line: CEPD0101_4_D06
• Germline Transmission: Earliest citation of germline transmission: J:188991
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMMTOOLS

Mutation description

• Allele Type: Targeted (Conditional ready, Inducible, Recombinase, Reporter)
• Mutation: Insertion Vector: L1L2_gt0
• Dmp1^{tm2(EGFP/cre/ERT2)Wtsi} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dmp1 (MGI:94910)

• Mutation details: According the the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted in the intron between exons 5 and 6. A single loxP site is inserted in the intron after exon 6. (J:188991)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dmp1 (mouse) Summary of all recombinase alleles driven by Dmp1. Comparative matrix view of recombinase activities Alliance mouse Dmp1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dmp1 Mutation: 42 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 1 reference(s)