Arf1^tm1.1Towa
Targeted Allele Detail

Summary

• Symbol: Arf1^tm1.1Towa
• Name: ARF GTPase 1; targeted mutation 1.1, Toshio Watanabe
• MGI ID: MGI:5697481
• Synonyms: Arf1^-
• Gene: Arf1 Location: Chr11:59102237-59119042 bp, - strand Genetic Position: Chr11, 37.05 cM, cytoband B2
• Alliance: Arf1^tm1.1Towa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220201
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP-flanked neomycin resistance (neo) cassette replaced the entire coding sequence of the gene. Mice were crossed to a Cre deleter strains (CAG-Cre-TG mice) to remove neo cassette. (J:220201)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arf1 Mutation: 14 strains or lines available

References

• Original: J:220201 Hayakawa N, et al., The ADP-ribosylation factor 1 gene is indispensable for mouse embryonic development after implantation. Biochem Biophys Res Commun. 2014 Oct 31;453(4):748-53
• All: 1 reference(s)