B3gat3^tm1Hkit
Targeted Allele Detail

Summary

• Symbol: B3gat3^tm1Hkit
• Name: beta-1,3-glucuronyltransferase 3; targeted mutation 1, Hiroshi Kitagawa
• MGI ID: MGI:5697553
• Synonyms: GlcAT-I^-
• Gene: B3gat3 Location: Chr19:8897740-8904600 bp, + strand Genetic Position: Chr19, 6.03 cM, cytoband A
• Alliance: B3gat3^tm1Hkit page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225032
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin selection cassette was inserted in reverse transcriptional orientation into an EcoRV site in GlcAT-I exon 2. (J:225032)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any B3gat3 Mutation: 8 strains or lines available

References

• Original: J:225032 Izumikawa T, et al., Impairment of embryonic cell division and glycosaminoglycan biosynthesis in glucuronyltransferase-I-deficient mice. J Biol Chem. 2010 Apr 16;285(16):12190-6
• All: 1 reference(s)