Tg(Sox10-ERT2/cre/ERT2)17Sor
Transgene Detail

Summary

• Symbol: Tg(Sox10-ERT2/cre/ERT2)17Sor
• Name: transgene insertion 17, Philippe Soriano
• MGI ID: MGI:5697877
• Synonyms: SECE17, Sox10ER^T2CreER^T2
• Transgene: Tg(Sox10-ERT2/cre/ERT2)17Sor Location: unknown
• Alliance: Tg(Sox10-ERT2/cre/ERT2)17Sor page

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Sox10-ERT2/cre/ERT2)17Sor expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Sox10

• Mutation details: The Multiple Species Conserved Sequence 4 (MCS 4) distal enhancer with a c-Fos minimal promoter drives neural crest cell and derivatives-specific expression of an inducible cre recombinase gene flanked by two modified estrogen receptors (ERT2/cre/ERT2) followed by a rabbit globin polyadenylation sequence. Two lines were generated with line 17 selected as the representative line. (J:226186)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Sox10 (species not specified) Summary of all recombinase alleles driven by Sox10. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:226186 He F, et al., Sox10ER(T2) CreER(T2) mice enable tracing of distinct neural crest cell populations. Dev Dyn. 2015 Nov;244(11):1394-403
• All: 1 reference(s)