Tg(Mpdz)1Kb
Transgene Detail

Summary

• Symbol: Tg(Mpdz)1Kb
• Name: transgene insertion 1, Kari Buck
• MGI ID: MGI:5698210
• Synonyms: Tg(RP23-119B7)^1KB
• Transgene: Tg(Mpdz)1Kb Location: unknown
• Alliance: Tg(Mpdz)1Kb page

Transgene origin

• Strain of Origin: C57BL/6 x DBA/2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mpdz)1Kb expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mpdz (MGI:1343489)

• Mutation details: A C57BL/6 strain mouse BAC clone (RPCI-23-119B7) that contains Mpdz as the only full-length coding gene, was used to inject zygotes. The 135 kb Mpdz coding sequence is positioned in the center of this BAC with an additional 16.0 kb upstream and 18.4 kb downstream of the gene contained within the consruct. (J:226456)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:226456 Milner LC, et al., Novel MPDZ/MUPP1 transgenic and knockdown models confirm Mpdz's role in ethanol withdrawal and support its role in voluntary ethanol consumption. Addict Biol. 2015 Jan;20(1):143-7
• All: 2 reference(s)