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Mawq1C57BL/6J
QTL Variant Detail
Summary
QTL variant: Mawq1C57BL/6J
Name: male adrenal weight QTL 1; C57BL/6J
MGI ID: MGI:5698445
QTL: Mawq1  Location: unknown  Genetic Position: Chr4, Syntenic
Variant
origin
Strain of Specimen:  C57BL/6J
Variant
description
Allele Type:    QTL
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:170709

Linkage analysis was performed on 64 BXD RI strains (n = 528) to identify QTL associated with adrenal weight in males.

QTL Mawq1 maps to 99.5 - 102.5 Mb on Chromosome 4 with a peak LOD score of 3.983 in linkage with male adrenal weight. C57BL/6J allelesincrease adrenal weight at the Mawq1 locus. The protein coding genes Lepr and Pde4b have been identified as potential Mawq1 candidate genes.

Suggestive QTL for male adrenal weight were mapped to chromosomes 2, 4, 10, 17, and X.

References
Original:  J:170709 Di Curzio DL, et al., The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory