Mir203^tm1.2Yir
Targeted Allele Detail

Summary

• Symbol: Mir203^tm1.2Yir
• Name: microRNA 203; targeted mutation 1.2, Rui Yi
• MGI ID: MGI:5698456
• Synonyms: miR-203^-
• Gene: Mir203 Location: Chr12:112097314-112097389 bp, + strand Genetic Position: Chr12, 61.14 cM
• Alliance: Mir203^tm1.2Yir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226044
• Parent Cell Line: CY2.4 (ES Cell)
• Strain of Origin: B6(Cg)-Tyr^c-2J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Cre mediated recombination removed the hairpin loop from Mir203^tm1.1Yir. In situ hybridization and qPCR verified the absence of transcript. (J:226044)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir203 Mutation: 4 strains or lines available

References

• Original: J:226044 Riemondy K, et al., MicroRNA-203 represses selection and expansion of oncogenic Hras transformed tumor initiating cells. Elife. 2015;4
• All: 1 reference(s)