Cbfb^tm1.1Ddg
Targeted Allele Detail

Summary

• Symbol: Cbfb^tm1.1Ddg
• Name: core binding factor beta; targeted mutation 1.1, David D Ginty
• MGI ID: MGI:5698722
• Synonyms: Cbfb^Flag
• Gene: Cbfb Location: Chr8:105897306-105944621 bp, + strand Genetic Position: Chr8, 53.04 cM
• Alliance: Cbfb^tm1.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226826
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: Sequences encoding an FRT-flanked neomycin selection cassette and a single Flag epitope were introduced immediately upstream of the translational start site of the gene. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:226826)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Cbfb Mutation: 36 strains or lines available

References

• Original: J:226826 Huang S, et al., Extrinsic and intrinsic signals converge on the Runx1/CBFbeta transcription factor for nonpeptidergic nociceptor maturation. Elife. 2015;4:e10874
• All: 1 reference(s)