Mc4r^Mhdahwe13
Chemically induced Allele Detail

Summary

• Symbol: Mc4r^Mhdahwe13
• Name: melanocortin 4 receptor; Martin Hrabe de Angelis heavy weight 13
• MGI ID: MGI:5699976
• Synonyms: HWE013Mc4rL54QMhda, Mc4r^L54QMhda
• Gene: Mc4r Location: Chr18:66990776-66993558 bp, - strand Genetic Position: Chr18, 39.72 cM, cytoband E1
• Alliance: Mc4r^Mhdahwe13 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: This mutation, discovered by its phenotype among the progeny of an ENU-treated male mouse, is an adenine-to-thymine substitution at nucleotide position 161 that results in the replacement of glutamine by leucine at amino acid position 54 of the protein. (J:82809)
• Inheritance: Dominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mc4r Mutation: 48 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)