Ccdc154^ntl
Spontaneous Allele Detail

Summary

• Symbol: Ccdc154^ntl
• Name: coiled-coil domain containing 154; new toothless
• MGI ID: MGI:5702426
• Gene: Ccdc154 Location: Chr17:25381435-25390887 bp, + strand Genetic Position: Chr17, 12.53 cM
• Alliance: Ccdc154^ntl page

Mutation origin

• Strain of Origin: 129S7/SvEvBrd

Mutation description

• Allele Type: Spontaneous (Null/knockout)
• Mutation: Deletion
• Mutation details: Genomic sequencing and southern blot analysis revealed a ~5 kb deletion including exons 1 - 6 of the gene in the mutant mice. (J:226596, J:244484)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc154 Mutation: 36 strains or lines available

References

• Original: J:226596 Lu X, et al., A new osteopetrosis mutant mouse strain (ntl) with odontoma-like proliferations and lack of tooth roots. Eur J Oral Sci. 2009 Dec;117(6):625-35
• All: 3 reference(s)