Serinc1^{Tn(sb-lacZ,GFP)1.7Tcb}
Transposon induced Allele Detail

Summary

• Symbol: Serinc1^{Tn(sb-lacZ,GFP)1.7Tcb}
• Name: serine incorporator 1; transposon insertion 1.7, Thomas Brodnicki
• MGI ID: MGI:5702669
• Synonyms: SB7, Serinc1^{Tn(sb-Trans-SA-IRESLacZ-CAG-GFP-SD:Neo)1.7Tcb}
• Gene: Serinc1 Location: Chr10:57391870-57408573 bp, - strand Genetic Position: Chr10, 29.19 cM
• Alliance: Serinc1^{Tn(sb-lacZ,GFP)1.7Tcb} page

Mutation origin

• Strain of Origin: NOD/ShiLt

Mutation description

• Allele Type: Transposon induced (Hypomorph)
• Mutation: Transposon insertion
• Mutation details: The activation of transposon concatemer TgTn(sb-lacZ,GFP)1Tcb with Tg(Prm-sb10)1Tcb inserted 4.6kb 5' of the gene. RT-PCR confirmed reduced transcript expression. (J:227341)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Serinc1 Mutation: 21 strains or lines available

References

• Original: J:227341 Elso CM, et al., Sleeping Beauty Transposon Mutagenesis as a Tool for Gene Discovery in the NOD Mouse Model of Type 1 Diabetes. G3 (Bethesda). 2015;5(12):2903-11
• All: 1 reference(s)