Tcim^tm1Icle
Targeted Allele Detail

Summary

• Symbol: Tcim^tm1Icle
• Name: transcriptional and immune response regulator; targeted mutation 1, Inchul Lee
• MGI ID: MGI:5702748
• Synonyms: Tc1^-
• Gene: Tcim Location: Chr8:24927188-24928962 bp, - strand Genetic Position: Chr8, 12.47 cM
• Alliance: Tcim^tm1Icle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217318
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A 1373 bp region including the entire gene was replaced with a PGK-neo cassette via homologous recombination. RT-PCR and Western blot analysis confirmed the deletion in homozygous mutant mice. (J:217318)

Generation of the Tcim^tm1Icle allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tcim Mutation: 9 strains or lines available

References

• Original: J:217318 Jung Y, et al., TC1(C8orf4) regulates hematopoietic stem/progenitor cells and hematopoiesis. PLoS One. 2014;9(6):e100311
• All: 1 reference(s)