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Trp63m1Mhda
Chemically induced Allele Detail
Summary
Symbol: Trp63m1Mhda
Name: transformation related protein 63; mutation 1, Martin Hrabe de Angelis
MGI ID: MGI:5702898
Synonyms: Trp63Y275*Mhda, Trp63Y275XMhda
Gene: Trp63  Location: Chr16:25502513-25710842 bp, + strand  Genetic Position: Chr16, 17.37 cM
Alliance: Trp63m1Mhda page
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsA T-to-A transversion at nucleotide position 825, in exon 6, results in replacement of a triplet encoding tyrosine at amino acid position 275 by a nonsense (termination) codon (Y275Ter; Tyr275Ter). (J:82809)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Trp63 Mutation:  60 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory