Dp(16Mir802-Zbtb21)3TybEmcf
Targeted Allele Detail

Summary

• Symbol: Dp(16Mir802-Zbtb21)3TybEmcf
• Name: duplication, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 3
• MGI ID: MGI:5703802
• Synonyms: Dp(16)3TybEmcf, Dp3Tyb
• Gene: Dp(16Mir802-Zbtb21)3TybEmcf Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227899
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted
• Mutations: Duplication, Insertion
• Dp(16Mir802-Zbtb21)3TybEmcf involves 95 genes/genome features (Gm15341, Gm15317, Gm22344 ...) View all
• Mutation details: An un-specified MICER vector and MHPN352i16 (16:97977263-16:97982380 Mb) were used to insert loxP sites proximal to Mir802 and distal to Zbtb21. Cre-mediated recombination duplicated the 4.9 Mb floxed by loxP sites. (J:227899)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Dp(16Mir802-Zbtb21)3TybEmcf Mutation: 2 strains or lines available

References

• Original: J:227899 Lana-Elola E, et al., Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 2016 Jan 14;5:e11614
• All: 6 reference(s)