Dp(16Mir802-Vps26c)4TybEmcf
Targeted Allele Detail

Summary

• Symbol: Dp(16Mir802-Vps26c)4TybEmcf
• Name: duplication, Chr 16, Victor Tybulewicz and Elizabeth M C Fisher 4
• MGI ID: MGI:5703804
• Synonyms: Dp(16)4TybEmcf, Dp(16Mir802-Dscr3)4TybEmcf, Dp4Tyb
• Gene: Dp(16Mir802-Vps26c)4TybEmcf Location: unknown Genetic Position: Chr16, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227899
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted
• Mutations: Duplication, Insertion
• Dp(16Mir802-Vps26c)4TybEmcf involves 33 genes/genome features (Gm23062, Gm41500, Gm22344 ...) View all
• Mutation details: An un-specified MICER vector and MHPP432c09 (16:94538615-16:94546849 Mb; mouse assembly GRCm38/mm10) located between Dscr3 and Dyrk1a were subjected to cre-mediated recombination to duplicate the sequence flanked by loxP sites. (J:227899)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Dp(16Mir802-Vps26c)4TybEmcf Mutation: 2 strains or lines available

References

• Original: J:227899 Lana-Elola E, et al., Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. Elife. 2016 Jan 14;5:e11614
• All: 3 reference(s)