Ncaph2^tm1.1Hiran
Targeted Allele Detail

Summary

• Symbol: Ncaph2^tm1.1Hiran
• Name: non-SMC condensin II complex, subunit H2; targeted mutation 1.1, Tatsuya Hirano
• MGI ID: MGI:5703865
• Synonyms: Ncaph2^flox, Ncaph2^tm1.1Itl
• Gene: Ncaph2 Location: Chr15:89239922-89257029 bp, + strand Genetic Position: Chr15, 44.84 cM
• Alliance: Ncaph2^tm1.1Hiran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222181
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A frt site, loxP site, neomycin selection cassette, a frt site, a loxP site were inserted upstream of exon 3 and a loxP site was inserted downstream of exon 8 via homologous recombination. The neomycin selection cassette was removed via flp-mediated recombination. (J:222181)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ncaph2 Mutation: 38 strains or lines available

References

• Original: J:222181 Nishide K, et al., Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. PLoS Genet. 2014 Dec;10(12):e1004847
• All: 1 reference(s)