Ncaph^tm1.1Hiran
Targeted Allele Detail

Summary

• Symbol: Ncaph^tm1.1Hiran
• Name: non-SMC condensin I complex, subunit H; targeted mutation 1.1, Tatsuya Hirano
• MGI ID: MGI:5703872
• Synonyms: Ncaph^flox, Ncaph^tm1.1Itl
• Gene: Ncaph Location: Chr2:126945729-126975857 bp, - strand Genetic Position: Chr2, 61.76 cM
• Alliance: Ncaph^tm1.1Hiran page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222181
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site upstream of exon 2, a frt site, a loxP site, a neomycin selection cassette, a frt site, and a loxP site were inserted downstream of exon 4 via homologous recombination. The neomycin selection cassette was removed via flp-mediated recombination. (J:222181)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ncaph Mutation: 30 strains or lines available

References

• Original: J:222181 Nishide K, et al., Overlapping and non-overlapping functions of condensins I and II in neural stem cell divisions. PLoS Genet. 2014 Dec;10(12):e1004847
• All: 1 reference(s)