Bmp10tm1.1(Gdf2)Minh
Targeted Allele Detail
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Symbol: |
Bmp10tm1.1(Gdf2)Minh |
Name: |
bone morphogenetic protein 10; targeted mutation 1.1, Minhong Yan |
MGI ID: |
MGI:5703977 |
Synonyms: |
Bmp109 |
Gene: |
Bmp10 Location: Chr6:87405976-87411494 bp, + strand Genetic Position: Chr6, 37.96 cM, cytoband D2
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Alliance: |
Bmp10tm1.1(Gdf2)Minh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:222016
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Parent Cell Line: |
C2 (Nagy) (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted (Inserted expressed sequence, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Bmp10tm1.1(Gdf2)Minh expresses
1 gene
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Mutation details: Exons 1 and 2 were replaced with the corresponding sequence from Gdf2. A loxP site was inserted upstream of exon 2 and an FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette.
(J:222016)
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Generation of the Bmp10tm1.1(Gdf2)Minh allele |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Bmp10 Mutation: |
22 strains or lines available
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Original: |
J:222016 Chen H, et al., Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11887-92 |
All: |
1 reference(s) |
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