Elp3^tm1.1Tac
Targeted Allele Detail

Summary

• Symbol: Elp3^tm1.1Tac
• Name: elongator acetyltransferase complex subunit 3; targeted mutation 1.1, Taconic
• MGI ID: MGI:5704311
• Synonyms: Elp3^loxp
• Gene: Elp3 Location: Chr14:65767898-65830524 bp, - strand Genetic Position: Chr14, 34.33 cM, cytoband D1
• Alliance: Elp3^tm1.1Tac page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227334
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 2 was floxed. Flp-mediated recombination removed the FRT-flanked puromycin resistance cassette inserted in intron 1. (J:227334)

Expression

In Mice Carrying this Mutation:	6 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Elp3 Mutation: 40 strains or lines available

References

• Original: J:227334 Ladang A, et al., Elp3 drives Wnt-dependent tumor initiation and regeneration in the intestine. J Exp Med. 2015 Nov 16;212(12):2057-75
• All: 8 reference(s)