Adgrg3^tm1Zgwg
Targeted Allele Detail

Summary

• Symbol: Adgrg3^tm1Zgwg
• Name: adhesion G protein-coupled receptor G3; targeted mutation 1, Zhugang Wang
• MGI ID: MGI:5704321
• Gene: Adgrg3 Location: Chr8:95744320-95771878 bp, + strand Genetic Position: Chr8, 47.12 cM
• Alliance: Adgrg3^tm1Zgwg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222670
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin resistance cassette replaced exons 1 and 2. Western blot analysis confirmed the absence of protein expression in the bone marrow. (J:222670)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adgrg3 Mutation: 42 strains or lines available

References

• Original: J:222670 Wang JJ, et al., Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision. Cell Death Dis. 2013;4:e853
• All: 3 reference(s)