About   Help   FAQ
Del(4Cyp2j13-Cyp2j5)1Brs
Targeted Allele Detail
Summary
Symbol: Del(4Cyp2j13-Cyp2j5)1Brs
Name: deletion, Chr 4, Brian Seed 1
MGI ID: MGI:5704342
Synonyms: Cyp2j-, Del1Brs, Del(4Cyp2j)1Brs
Gene: Del(4Cyp2j13-Cyp2j5)1Brs  Location: unknown  Genetic Position: Chr4, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223128
Parent Cell Line:  J-A18 (B6-albino) (ES Cell)
Strain of Origin:  B6(Cg)-Tyrc-2J/J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion, Intragenic deletion
  Del(4Cyp2j13-Cyp2j5)1Brs involves 9 genes/genome features (2900072D07Rik, Cyp2j13, Cyp2j12 ...) View all
 
Mutation detailsTP901 integrase-mediated recombination of an attP3 site followed by a neomycin resistance gene and attP2 site introduced downstream of Cyp2j13 and an attP3 site followed by an ampicillin resistance gene, blasticidin resistance gene and attP2 site inserted upstream of Cyp2j5 deleted the intervening sequence. The neomycin, ampicillin and blasticidin resistance cassettes remain. (J:223128)
Construction of the Del(4Cyp2j13-Cyp2j5)1Brs deletion
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 3 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Del(4Cyp2j13-Cyp2j5)1Brs Mutation:  0 strains or lines available
References
Original:  J:223128 Zhou GL, et al., Deletion of the murine cytochrome P450 Cyp2j locus by fused BAC-mediated recombination identifies a role for Cyp2j in the pulmonary vascular response to hypoxia. PLoS Genet. 2013 Nov;9(11):e1003950
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory