Kdr^tm1Ykub
Targeted Allele Detail

Summary

• Symbol: Kdr^tm1Ykub
• Name: kinase insert domain protein receptor; targeted mutation 1, Yoshiaki Kubota
• MGI ID: MGI:5705394
• Synonyms: Vegfr2^deltas
• Gene: Kdr Location: Chr5:76093487-76139118 bp, - strand Genetic Position: Chr5, 40.23 cM
• Alliance: Kdr^tm1Ykub page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217533
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Deletion of exon 13 prevents the production of the soluble isoform. Production of the membrane-bound isoform is not affected. (J:217533)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdr Mutation: 74 strains or lines available

References

• Original: J:217533 Okabe K, et al., Neurons limit angiogenesis by titrating VEGF in retina. Cell. 2014 Oct 23;159(3):584-96
• All: 1 reference(s)