Mlxip^tm1.2Lchan
Targeted Allele Detail

Summary

• Symbol: Mlxip^tm1.2Lchan
• Name: MLX interacting protein; targeted mutation 1.2, Lawrence Chan
• MGI ID: MGI:5705614
• Gene: Mlxip Location: Chr5:123532861-123595995 bp, + strand Genetic Position: Chr5, 62.95 cM
• Alliance: Mlxip^tm1.2Lchan page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:217834
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted upstream of exon 2 and a loxP site was inserted downstream of exon 2 via homologous recombination. Cre mediated recombination removed the neo cassette and exon 2. (J:217834)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mlxip Mutation: 24 strains or lines available

References

• Original: J:217834 Imamura M, et al., MondoA deficiency enhances sprint performance in mice. Biochem J. 2014 Nov 15;464(1):35-48
• All: 1 reference(s)