Dhx30^Gt(IG)1Zsj
Gene trapped Allele Detail

Summary

• Symbol: Dhx30^Gt(IG)1Zsj
• Name: DExH-box helicase 30; gene trap 1, Zai-Si Ji
• MGI ID: MGI:5705780
• Gene: Dhx30 Location: Chr9:109913387-109946728 bp, - strand Genetic Position: Chr9, 59.86 cM
• Alliance: Dhx30^Gt(IG)1Zsj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218057
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector
• Mutation details: A gene trap vector consisting of a splicing acceptor site of the mouse Fgf4; an oligomer with three different frame termination codons; an IRES; Geo, which is the fusion gene of E. coli LacZ gene and neomycin resistance gene and an SV40 early mRNA polyadenylation signal was inserted in the middle of the 3'-most exon (3705-3723). The insertion also produced a 19 base deletion. (J:218057)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dhx30 Mutation: 104 strains or lines available

References

• Original: J:218057 Zheng HJ, et al., The Novel Helicase helG (DHX30) Is Expressed During Gastrulation in Mice and Has a Structure Similar to a Human DExH Box Helicase. Stem Cells Dev. 2015 Feb 1;24(3):372-83
• All: 1 reference(s)