Opn1sw^tm1.2Mnei
Targeted Allele Detail

Summary

• Symbol: Opn1sw^tm1.2Mnei
• Name: opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan); targeted mutation 1.2, Maureen Neitz
• MGI ID: MGI:5706728
• Gene: Opn1sw Location: Chr6:29376670-29380512 bp, - strand Genetic Position: Chr6, 12.36 cM
• Alliance: Opn1sw^tm1.2Mnei page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228345
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neomycin cassette flanked by one loxP site in intron 4 and a second loxP site in intron 1 were inserted via homologous recombination. Recombinase activities removed exons 2-4 and neo cassette. (J:228345)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Opn1sw Mutation: 22 strains or lines available

References

• Original: J:228345 Greenwald SH, et al., S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant. Vis Neurosci. 2014 Jan;31(1):25-37
• All: 2 reference(s)