Tg(Sftpc-Grem1)105Mmyl
Transgene Detail

Summary

• Symbol: Tg(Sftpc-Grem1)105Mmyl
• Name: transgene insertion 105, Marjukka Myllarniemi
• MGI ID: MGI:5707177
• Synonyms: SPC-lox-gremlin1
• Transgene: Tg(Sftpc-Grem1)105Mmyl Location: unknown
• Alliance: Tg(Sftpc-Grem1)105Mmyl page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Sftpc-Grem1)105Mmyl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Grem1

• Mutation details: This transgene contains the surfactant associated protein C (Sftpc) promoter followed by a loxP-flanked neomycin resistance cassette with a strong translation termination (STOP) signal and the gremlin 1, DAN family BMP antagonist (Grem1) coding sequence. Deletion of the floxed sequence by Cre recombinase in transgenic mice results in Grem1 expression in lung type II epithelial cells. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 2 reference(s)