Ntrk3^tm2.1Ddg
Targeted Allele Detail

Summary

• Symbol: Ntrk3^tm2.1Ddg
• Name: neurotrophic tyrosine kinase, receptor, type 3; targeted mutation 2.1, David D Ginty
• MGI ID: MGI:5707201
• Synonyms: TrkC^tdTomato
• Gene: Ntrk3 Location: Chr7:77825711-78228865 bp, - strand Genetic Position: Chr7, 44.01 cM
• Alliance: Ntrk3^tm2.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227979
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A myristolated dTomato reporter gene and an FRT-flanked neomycin resistance cassette were inserted at the translation initiation site replacing the coding sequence in exon 1. Flp-mediated recombination removed the selection cassette. (J:227979)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ntrk3 Mutation: 67 strains or lines available

References

• Original: J:227979 Bai L, et al., Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking. Cell. 2015 Dec 17;163(7):1783-95
• All: 7 reference(s)