Ankrd1^tm1.2Jmda
Targeted Allele Detail

Summary

• Symbol: Ankrd1^tm1.2Jmda
• Name: ankyrin repeat domain 1; targeted mutation 1.2, Jeffrey M Davidson
• MGI ID: MGI:5707279
• Gene: Ankrd1 Location: Chr19:36089365-36097244 bp, - strand Genetic Position: Chr19, 30.52 cM, cytoband C3
• Alliance: Ankrd1^tm1.2Jmda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:218253
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted 600 bp upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted in intron 2 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 2. (J:218253)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ankrd1 Mutation: 21 strains or lines available

References

• Original: J:218253 Samaras SE, et al., Global deletion of Ankrd1 results in a wound-healing phenotype associated with dermal fibroblast dysfunction. Am J Pathol. 2015 Jan;185(1):96-109
• All: 2 reference(s)