Ubiad1^tm1.1Thka
Targeted Allele Detail

Summary

• Symbol: Ubiad1^tm1.1Thka
• Name: UbiA prenyltransferase domain containing 1; targeted mutation 1.1, Toshio Okano
• MGI ID: MGI:5707728
• Gene: Ubiad1 Location: Chr4:148518952-148529217 bp, - strand Genetic Position: Chr4, 78.76 cM, cytoband E1
• Alliance: Ubiad1^tm1.1Thka page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221005
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 1. Cre-mediated recombination removed exon 1 and the selection cassette. (J:221005)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubiad1 Mutation: 25 strains or lines available

References

• Original: J:221005 Nakagawa K, et al., Vitamin K2 biosynthetic enzyme, UBIAD1 is essential for embryonic development of mice. PLoS One. 2014;9(8):e104078
• All: 1 reference(s)