Retsattm1Kpal
Targeted Allele Detail
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Symbol: |
Retsattm1Kpal |
Name: |
retinol saturase (all trans retinol 13,14 reductase); targeted mutation 1, Krzysztof Palczewski |
MGI ID: |
MGI:5708113 |
Synonyms: |
RetSat- |
Gene: |
Retsat Location: Chr6:72575585-72584471 bp, + strand Genetic Position: Chr6, 32.27 cM, cytoband C3
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Alliance: |
Retsattm1Kpal page
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Germline Transmission: |
Earliest citation of germline transmission:
J:222367
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 1 was replaced with a neomycin selection cassette. RT-PCR of RNA isolated from the liver of homozygous mice using primers directed against exon 1 and exon 4 shows that there was no detectable message expressed from this allele. Immunoblotting of liver lysates and immunohistochemistry of liver sections from homozygous mice indicates that the encoded protein is not detectable in homozygous mice.
(J:222367)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Retsat Mutation: |
23 strains or lines available
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Original: |
J:222367 Moise AR, et al., Increased adiposity in the retinol saturase-knockout mouse. FASEB J. 2010 Apr;24(4):1261-70 |
All: |
4 reference(s) |
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