Enpp2^tm1.2Vart
Targeted Allele Detail

Summary

• Symbol: Enpp2^tm1.2Vart
• Name: ectonucleotide pyrophosphatase/phosphodiesterase 2; targeted mutation 1.2, Vassilis Aidinis
• MGI ID: MGI:5708147
• Synonyms: Enpp2^flox
• Gene: Enpp2 Location: Chr15:54702297-54816284 bp, - strand Genetic Position: Chr15, 21.6 cM, cytoband D2
• Alliance: Enpp2^tm1.2Vart page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: This allele was derived from Enpp2^tm1Vart by Cre recombinase excision of the loxP-flanked neomycin resistance cassette, leaving single loxP sites upstream of exon 1 and downstream of exon 2. The absence of the selection cassette was confirmed by PCR analysis. (J:159118)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Enpp2 Mutation: 77 strains or lines available

References

• Original: J:159118 Fotopoulou S, et al., ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol. 2010 Mar 15;339(2):451-64
• All: 6 reference(s)