Ank2^tm1.1Pmoh
Targeted Allele Detail

Summary

• Symbol: Ank2^tm1.1Pmoh
• Name: ankyrin 2, brain; targeted mutation 1.1, Peter J Mohler
• MGI ID: MGI:5708349
• Synonyms: Ank2^F
• Gene: Ank2 Location: Chr3:126715261-127292999 bp, - strand Genetic Position: Chr3, 56.07 cM
• Alliance: Ank2^tm1.1Pmoh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:219411
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 24 was floxed via homologous recombination, the construct also includes an FRT-flanked neomycin cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:219411)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ank2 Mutation: 185 strains or lines available

References

• Original: J:219411 Chang KJ, et al., Glial ankyrins facilitate paranodal axoglial junction assembly. Nat Neurosci. 2014 Dec;17(12):1673-81
• All: 10 reference(s)