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Gpr18tm1.1Cys
Targeted Allele Detail
Summary
Symbol: Gpr18tm1.1Cys
Name: G protein-coupled receptor 18; targeted mutation 1.1, Jason G Cyster
MGI ID: MGI:5708707
Gene: Gpr18  Location: Chr14:122148846-122153300 bp, - strand  Genetic Position: Chr14, 65.86 cM
Alliance: Gpr18tm1.1Cys page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219661
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.4kb region including the single exon was floxed and an FRT flanked neo gene was inserted via homologous recombination. Cre mediated recombination removed the single exon. (J:219661)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gpr18 Mutation:  20 strains or lines available
References
Original:  J:219661 Wang X, et al., GPR18 is required for a normal CD8alphaalpha intestinal intraepithelial lymphocyte compartment. J Exp Med. 2014 Nov 17;211(12):2351-9
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory