Samd8^tm1Jia
Targeted Allele Detail

Summary

• Symbol: Samd8^tm1Jia
• Name: sterile alpha motif domain containing 8; targeted mutation 1, Xian-Cheng Jiang
• MGI ID: MGI:5749225
• Gene: Samd8 Location: Chr14:21800599-21848794 bp, + strand Genetic Position: Chr14, 11.86 cM, cytoband B
• Alliance: Samd8^tm1Jia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220024
• Parent Cell Line: PTL1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a stop cassette that includes a slice acceptor site, pgk-neo cassette and tri-phase translational stop codon via homologous recombination. (J:220024)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Samd8 Mutation: 31 strains or lines available

References

• Original: J:220024 Ding T, et al., All members in the sphingomyelin synthase gene family have ceramide phosphoethanolamine synthase activity. J Lipid Res. 2015 Mar;56(3):537-45
• All: 2 reference(s)