Tg(Ttr-SMYD3)1Ital
Transgene Detail

Summary

• Symbol: Tg(Ttr-SMYD3)1Ital
• Name: transgene insertion 1, Iannis Talianidis
• MGI ID: MGI:5749481
• Transgene: Tg(Ttr-SMYD3)1Ital Location: unknown
• Alliance: Tg(Ttr-SMYD3)1Ital page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ttr-SMYD3)1Ital expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SMYD3 (64754)

  Smyd3

  (MGI:1916976)

• Mutation details: The transgene contains the mouse transthyretin promoter driving expression of human SMYD3 (SET and MYND domain containing 3) with three hemagglutinin (HA) and three FLAG epitope tags at its C- and N-termini, respectively. Hepatic expression of the human protein is at least 15-fold that of the endogenous mouse protein. (J:82809)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)