Wnt6^tm1(cre)Mrc
Targeted Allele Detail

Summary

• Symbol: Wnt6^tm1(cre)Mrc
• Name: wingless-type MMTV integration site family, member 6; targeted mutation 1, Mario R Capecchi
• MGI ID: MGI:5749680
• Synonyms: W6cre, Wnt6IresCre
• Gene: Wnt6 Location: Chr1:74811051-74824481 bp, + strand Genetic Position: Chr1, 38.54 cM
• Alliance: Wnt6^tm1(cre)Mrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227707
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Wnt6^tm1(cre)Mrc expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Wnt6 (MGI:98960)

• An IRES sequence and cre recombinase gene were inserted into the locus. (J:227707)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Wnt6 (mouse) Summary of all recombinase alleles driven by Wnt6. Comparative matrix view of recombinase activities Alliance mouse Wnt6 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt6 Mutation: 13 strains or lines available

References

• Original: J:227707 Carroll LS, et al., Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/beta-catenin signaling. Development. 2015 Dec 1;142(23):4056-67
• All: 1 reference(s)