Ccdc3^tm1Ish
Targeted Allele Detail

Summary

• Symbol: Ccdc3^tm1Ish
• Name: coiled-coil domain containing 3; targeted mutation 1, Iichiro Shimomura
• MGI ID: MGI:5749736
• Synonyms: Favine^-
• Gene: Ccdc3 Location: Chr2:5142587-5235682 bp, + strand Genetic Position: Chr2, 3.25 cM, cytoband A1
• Alliance: Ccdc3^tm1Ish page

Decreased epididymal and subcutaneous adipose tissue weight and smaller adiopocyte size in Ccdc3^tm1Ish/Ccdc3^tm1Ish mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220560
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A genomic region including exon 1 and most of exon 2 was replaced with a floxed neo cassette via homologous recombination. (J:220560)

Generation of the Ccdc3^tm1Ish allele

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccdc3 Mutation: 25 strains or lines available

References

• Original: J:220560 Kobayashi S, et al., Fat/Vessel-derived Secretory Protein (Favine)/CCDC3 Is Involved in Lipid Accumulation. J Biol Chem. 2015 Mar 20;290(12):7443-51
• All: 2 reference(s)