Lmr4b^BALB/cHeA
QTL Variant Detail

Summary

• QTL variant: Lmr4b^BALB/cHeA
• Name: leishmaniasis resistance 4b; BALB/cHeA
• MGI ID: MGI:5750129
• QTL: Lmr4b Location: Chr6:113324286-113324483 bp Genetic Position: Chr6, Syntenic

Variant origin

• Strain of Specimen: BALB/cHeA

Variant description

• Allele Type: QTL

Notes

Lmr4b, mapping to D6Mit10 was identified in interaction with Lmr5f (D10Mit25), corrected p=0.011. Homozygous BALB/c alleles at Lmr4b and at Lmr5f were associated with increased IFN-gamma levels.

References

• Original: J:82715 Lipoldova M, et al., Susceptibility to Leishmania major infection in mice: multiple loci and heterogeneity of immunopathological phenotypes. Genes Immun. 2000 Feb;1(3):200-6
• All: 1 reference(s)