Gfra1^tm1.1Wql
Targeted Allele Detail

Summary

• Symbol: Gfra1^tm1.1Wql
• Name: glial cell line derived neurotrophic factor family receptor alpha 1; targeted mutation 1.1, Wenqin Luo
• MGI ID: MGI:5750220
• Gene: Gfra1 Location: Chr19:58224036-58444341 bp, - strand Genetic Position: Chr19, 54.18 cM, cytoband D2-D3
• Alliance: Gfra1^tm1.1Wql page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:220812
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 6 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:220812)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gfra1 Mutation: 33 strains or lines available

References

• Original: J:220812 Fleming MS, et al., Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors. Elife. 2015;4
• All: 2 reference(s)