Tg(Tek-Npr1)#Kkan
Transgene Detail

Summary

• Symbol: Tg(Tek-Npr1)#Kkan
• Name: transgene insertion, Kenji Kangawa
• MGI ID: MGI:5750460
• Synonyms: EC GC-A-Tg
• Transgene: Tg(Tek-Npr1)#Kkan Location: unknown
• Alliance: Tg(Tek-Npr1)#Kkan page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Tek-Npr1)#Kkan expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Npr1 (MGI:97371)

• Mutation details: A 12.1 kb fragment of the mouse Tek gene including the promoter, enhancer and exons 1-3 of the 5' UTR drives expression of a mouse Npr1 cDNA in the vascular endothelium. (J:220676)

Schematic diagram of the construct used to produce the Tg(Tek-Npr1)#Kkan trangenic mouse

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:220676 Nojiri T, et al., Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells. [RETRACTED}. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4086-91
• All: 1 reference(s)