Lmna^tm4Stw
Targeted Allele Detail

Summary

• Symbol: Lmna^tm4Stw
• Name: lamin A; targeted mutation 4, Colin L Stewart
• MGI ID: MGI:5750954
• Synonyms: Lmna^FL
• Gene: Lmna Location: Chr3:88388455-88413842 bp, - strand Genetic Position: Chr3, 38.84 cM
• Alliance: Lmna^tm4Stw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:193454
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 10 and a loxP site was inserted in the 3' UTR before exon 12. (J:193454, J:220874)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lmna Mutation: 84 strains or lines available

References

• Original: J:193454 Solovei I, et al., LBR and Lamin A/C Sequentially Tether Peripheral Heterochromatin and Inversely Regulate Differentiation. Cell. 2013 Jan 31;152(3):584-98
• All: 4 reference(s)