Tg(PER3)L474Ljp
Transgene Detail

Summary

• Symbol: Tg(PER3)L474Ljp
• Name: transgene insertion L474, Louis Ptacek
• MGI ID: MGI:5751206
• Synonyms: hPER3-WT
• Transgene: Tg(PER3)L474Ljp Location: unknown Genetic Position: ChrY, Syntenic
• Alliance: Tg(PER3)L474Ljp page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(PER3)L474Ljp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PER3 (8863)

  Per3	(MGI:1277134)

• Mutation details: The transgenic construct contains the entire human PER3 gene from BAC clone RP11-417D2 (CHORI). Founder line L474 carries two copies of the transgene on the Y chromosome. (J:229233)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:229233 Zhang L, et al., A PERIOD3 variant causes a circadian phenotype and is associated with a seasonal mood trait. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):E1536-44
• All: 1 reference(s)