Rgs18^tm1.1Ics
Targeted Allele Detail

Summary

• Symbol: Rgs18^tm1.1Ics
• Name: regulator of G-protein signaling 18; targeted mutation 1.1, Mouse Clinical Institute
• MGI ID: MGI:5751583
• Gene: Rgs18 Location: Chr1:144628430-144651165 bp, - strand Genetic Position: Chr1, 62.99 cM
• Alliance: Rgs18^tm1.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225296
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 4. A floxed neomycin resistance cassette was inserted downstream of exon 4. Cre-mediated recombination removed exon 4. (J:225296)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgs18 Mutation: 24 strains or lines available

References

• Original: J:225296 Delesque-Touchard N, et al., Regulator of G-protein signaling 18 controls both platelet generation and function. PLoS One. 2014;9(11):e113215
• All: 1 reference(s)