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Otud5tm1Vmd
Targeted Allele Detail
Summary
Symbol: Otud5tm1Vmd
Name: OTU domain containing 5; targeted mutation 1, Vishva M Dixit
MGI ID: MGI:5752247
Synonyms: Dubafl
Gene: Otud5  Location: ChrX:7707603-7742865 bp, + strand  Genetic Position: ChrX, 3.54 cM
Alliance: Otud5tm1Vmd page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:229517
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. (J:219495, J:229517)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Otud5 Mutation:  9 strains or lines available
References
Original:  J:229517 Huang OW, et al., Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat Struct Mol Biol. 2012 Feb;19(2):171-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory